Basic Information
VIS ID
TVIS44003956
Fusion event
HTLV-1-SLC9A9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q24
Reference genome
GRCh37/hg19
Start
143297883/143579041 (Hg38)
End
143297883/143579041 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC9A9
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-let-7g/Upstream/9141135; hsa-mir-1224/Downstream/7986835;
Nearest TSS
ENST00000440867/Upstream/197703; ENST00000491798/Downstream/119108;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/457045, chr3-CpG: 217/Downstream/391850
Upstream sequence
TCAGTAAACATTTTTATATTGGAAGGGTCATAAAGAATATTGTTTCTGAGCAAACTAGGCATTAAAACATGGTAGGTGTATAAGGAATCTGCTGAGAAGA
Downstream sequence
TAGATAACTGTGAATTATTTAGTGGCCATATGTCTTCAGTGCTGTTATATATTCACAGATGTTCCTGATAAAAAGTGCACTTTTATGGCCTGTGCACAAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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