Basic Information
VIS ID
TVIS44003961
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
81630868/80921151 (Hg38)
End
81630868/80921151 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/2381842; hsa-mir-1202/Downstream/9391591;
Nearest TSS
ENST00000381078/Upstream/454193; ENST00000614959/Downstream/630535;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/814182, chr6-CpG: 231/Downstream/830265
Nearby gene
BCKDHB(+574881) ;
Nearest cancer related gene
BCKDHB(OG, +574881) ;
Upstream sequence
CTGAAATGATTAAACATAATATGAGTAAAAATGACTGAAACTGTAATAGATTTTTGAAGATTATTTGTGAGGCTAGGTAGAAACCATTTTATGTTACAGA
Downstream sequence
ATGTTTCCATTGTTAATAAGACCAAAGTATCTCAGAACTAACAGAAGTGTAGTTTCTCTCCCTCTGCCTTAGTAGAAGATGTGAAAGTGCCATGACTATC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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