Basic Information
VIS ID
TVIS44003964
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
141133763/141754196 (Hg38)
End
141133763/141754196 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/1106270; hsa-mir-103a-1/Downstream/1925664;
Nearest TSS
ENST00000502646/Upstream/71975; ENST00000506775/Downstream/72129;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/425, chr5-CpG: 102/Downstream/95169
Nearby gene
ARAP3(-71963) ;
Upstream sequence
CACTTTTTCTTCCTCCTGGCAGTCTCGCGTTGGACTCTTTATCCCTGTGTGTCTTGCATACACTCTCTGTCTCTCTCCAATGCCTTCCCTTTCACTATCA
Downstream sequence
TCTCCTTTCTTACTCGGGTCAGAATGCCTCCGAGATGTGTGCCAGGAGCCACCTCTTGTTCAAGGTTGAGAAGTAATTCTGCCCCGGGACTCTGGTTCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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