Basic Information
VIS ID
TVIS44003996
Fusion event
HTLV-1-MIR5009 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
29179212/27806893 (Hg38)
End
29179212/27806893 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR5009
Nearest miRNA
hsa-let-7c/Upstream/852850; hsa-mir-3197/Downstream/2568401;
Nearest TSS
ENST00000624081/Upstream/82094; ENST00000433344/Downstream/148029;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/662906, chr21-CpG: 29/Downstream/1078210
Upstream sequence
CCAAATTCTTTTTGAGTAACTATTTCCTGTATTCATATTTTGTCTACTCACTTTATTCCTCAAAATTTTTCAAACTAATATATCTACTGTTTTATCTCAG
Downstream sequence
GTTCTTAGCCTCAACTATTCAGTAGCATTCAATCTATTAAACTGTCTTTAAATTATCCCTGCTTCTATAATCATCCCATTGGTGGAAACATTTATTTTCC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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