Basic Information
VIS ID
TVIS44004014
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
GRCh37/hg19
Start
226244564/226056863 (Hg38)
End
226244564/226056863 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/134721; hsa-mir-1182/Downstream/1884727;
Nearest TSS
ENST00000473358/Upstream/57532; ENST00000366814/Downstream/4988;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/57228, chr1-CpG: 171/Downstream/4893
Nearby gene
H3F3A(+5844) ;
Upstream sequence
tttgagaccagcctggccaacatggcaaaaccctgtctctattgaaaatacaaaaaaattagctgggcatggtggcacatgcctgtaattccagctactt
Downstream sequence
gggaggctgaggcaggagaattgcttgaacctgggaggcggaggttgcagtgagcagcgatcacaccactgcattccagcctggaccacagagtgagact
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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