Basic Information
VIS ID
TVIS44004038
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
83406152/81646396 (Hg38)
End
83406152/81646396 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/6093843; hsa-mir-107/Downstream/4618298;
Nearest TSS
ENST00000439456/Upstream/996599; ENST00000404547/Downstream/228918;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1109960, chr10-CpG: 149/Downstream/227897
Nearby gene
NRG3(+228918) ;
Upstream sequence
tttatctggtaaaattataatcctgttctatctgtgcctatgttcataaagaggtaggtagttggaacaaaacacaaaacctagctaatggcctcattaa
Downstream sequence
atacatgaccatgggtctcaaatcaacacctaacaatgctcaacaactgtactccacttagactacctattagctctcttttctttattaagtgactttt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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