Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene23008900228670522298106322886684228896262289523822896894228920162289295922930698229315142289142122891832229341452293451622918073229184272291929822919447229172142291727322937976
Basic Information
VIS ID
TVIS44004042
Fusion event
HTLV-1-CYFIP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
22935090/22937976 (Hg38)
End
22935090/22937976 (Hg38)
Orient
+
Location type
Intronic
Target gene
CYFIP1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-185-5p
Nearest miRNA
hsa-mir-1268a/Upstream/712647; hsa-mir-10393/Downstream/259851;
Nearest TSS
ENST00000557528/Upstream/11961; ENST00000562295/Downstream/9011;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/9911, chr15-CpG: 197/Downstream/41093
Upstream sequence
CCCACCAGCCCAGCCCCCAGACTCCTCCTGAGCAGGGGagcactgtccacggagtgctttgtgacagcagaaacgttgtgtctgcaccggctggtgtggg
Downstream sequence
agccctggccatgagcccctgcggagcactggagcatgcaggtggctagtccacgttaagaatttttagtttgtgactgggcacggtggctcatgcctgt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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