Basic Information
VIS ID
TVIS44004055
Fusion event
HTLV-1-IL12A-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.33
Reference genome
GRCh37/hg19
Start
159701385/159983597 (Hg38)
End
159701385/159983597 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA3D
Target gene
IL12A-AS1
Nearest miRNA
hsa-let-7g/Upstream/700863; hsa-mir-1224/Downstream/420991;
Nearest TSS
ENST00000440867/Upstream/94805; ENST00000480088/Downstream/5153;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/218363, chr3-CpG: 52/Downstream/5106
Upstream sequence
aggccaaggcaggcagatcacgaggtcaggagataaagaccaacctgggtaacacggtgaaaccctgtctctactaaaaatacaagaaaattagccaggt
Downstream sequence
gtggtggcagccgcctgtagtcccagctgctcgggaggctgaggcaggagaatggcatgaacctgggaggcaaagcttgcagtgagccaagattgagcca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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