Basic Information
VIS ID
TVIS44004063
Fusion event
HTLV-1-SLC22A20P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
65000818/65233347 (Hg38)
End
65000818/65233347 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
SLC22A20P
Nearest miRNA
hsa-mir-10392/Upstream/103369; hsa-let-7a-2/Downstream/211111;
Nearest TSS
ENST00000527297/Upstream/24203; ENST00000532391/Downstream/28415;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/7334, chr11-CpG: 81/Downstream/28222
Upstream sequence
CCCCGGCCATGCTGGTGGCCACCGCCACCATGATTTACGTGGGCCGCCGTGCCACGGTGGCCTCCTTCCTCATCCTGGCCGGGCTCATGGTGATCGCCAA
Downstream sequence
CATGTTTGTGCCAGAAGGTGAGTCACCCACTTCTGCCCTTGCTGCACACCAAGAACTGGGAGCCTCTGGGGTCTGGTAGACAACAAATTTCACATGGCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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