Basic Information
VIS ID
TVIS44004071
Fusion event
HTLV-1-BCAT2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49313674/48810417 (Hg38)
End
49313674/48810417 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
BCAT2
miRNAs that regulate target gene
hsa-mir-32-5p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-92b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10395/Upstream/1583396; hsa-let-7e/Downstream/199489;
Nearest TSS
ENST00000633603/Upstream/2625; ENST00000600406/Downstream/499;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/10556, chr19-CpG: 43/Downstream/423
Upstream sequence
agaaaccttgttctctgaaatcatagactctgggaaacgctgctgctgtttgacatcgcacagtcagaagggatcgtctcagccagcctgcagcatctgt
Downstream sequence
cactttgaccatgagacgctgcctcgatttccaatccaggtgcaaagcttcagataggagtttgggaagcacagcaatccccatctcttatttttttcaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate