Basic Information
VIS ID
TVIS44004079
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
9367806/9273949 (Hg38)
End
9367806/9273949 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/3641383; hsa-mir-11401/Downstream/2032491;
Nearest TSS
ENST00000527434/Upstream/166775; ENST00000564305/Downstream/81639;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/181117, chr16-CpG: 282/Downstream/906137
Nearby gene
MIR548X(No orient, 39003)
Upstream sequence
CTGCTCGGACACATGGGCCTCTACTTCCACGAAAAGCTATAGGATTCCCCTAGATTCGAATTAATTGCTTCCTTCTTGTGGAGCTCATGGGACTTCATTC
Downstream sequence
ATACCTGTCACGATCCTTAACAACATAACAATGTTGTAAATATTAGTATTATAGTGTATATGTTAGGCCCCTtcccccattcatttctgagcttctttag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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