VISDB Viral Integration Site DataBase

VIS ID

TVIS44004083

Fusion event

HTLV-1-POLR3A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q22.3

Reference genome

Start

End

79780186/78020428 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-769-3p ; hsa-mir-10a-5p ; hsa-mir-92a-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-331-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-556-5p ; hsa-mir-512-3p ; hsa-mir-4678 ; hsa-mir-449b-3p ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-640 ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-1281 ; hsa-mir-6777-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-4701-5p ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-4775 ; hsa-mir-138-2-3p ; hsa-mir-4735-5p ; hsa-mir-500b-3p ; hsa-mir-590-3p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-548s ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-378a-5p ; hsa-mir-197-3p ; hsa-mir-193b-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-483-5p ; hsa-mir-1273f ; hsa-mir-1289 ; hsa-mir-143-3p ; hsa-mir-3198 ; hsa-mir-4251 ; hsa-mir-4294 ; hsa-mir-4303 ; hsa-mir-4309 ; hsa-mir-4329 ; hsa-mir-4534 ; hsa-mir-4708-5p ; hsa-mir-4762-3p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-6514-5p ; hsa-mir-6761-5p ; hsa-mir-8082

Nearest miRNA

hsa-mir-1265/Upstream/2467875; hsa-mir-107/Downstream/8244266;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/93136, chr10-CpG: 26/Downstream/8952

Upstream sequence

ttttttaaaaaattagttaggcatagtggtgtgcatgtgtagtcctagctactcgggaggctgaggcataagaatggcttgagcccaggagtttgaggtt

Downstream sequence

acagtgagccatgagcacaccactgcacttcggcctgggtgacagggcgagagtctgtctcttaaaaaaaaaaaaCCAggccggatgcggtggctcatac