Basic Information
VIS ID
TVIS44004086
Fusion event
HTLV-1-CCDC130 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.13
Reference genome
GRCh37/hg19
Start
13844652/13733838 (Hg38)
End
13844652/13733838 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
CCDC130
Nearest miRNA
hsa-mir-10395/Upstream/793298; hsa-let-7e/Downstream/102449;
Nearest TSS
ENST00000633603/Upstream/2071; ENST00000588809/Downstream/13941;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/31053, chr19-CpG: 56/Downstream/13794
Nearby gene
CCDC130(+14101) ;
Upstream sequence
acattagacgccatgaacactccctcccaacccaatttgtcacaaccaaaaatgtctgcagacattgcccctgaaggggtgaagatggctcctattgaga
Downstream sequence
aacactgGCCATGAGCCAAGAATTAAAAGAGAGAAATCTGTTAGTTTTCACTAAATAGATTTGAATTCTTTATTTTAttttattgtttttgtttcatttt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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