Basic Information
VIS ID
TVIS44004090
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
127451684/126439439 (Hg38)
End
127451684/126439439 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/1617381; hsa-mir-10400/Downstream/1356523;
Nearest TSS
ENST00000518652/Upstream/113944; ENST00000520171/Downstream/34750;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1007241, chr8-CpG: 180/Downstream/116992
Nearby gene
LOC101927657(No orient, 109906)
Upstream sequence
AGTATTCTATGGTAGAGTAGTATCAAACATACATTGATTTAATCTGCCCATATTCAACTATCCATGCTTGGCCAAAAAATAAAGAGAGAAAATCATAAtt
Downstream sequence
ttcattgaacatgagcccctaatgcaagccaattacttcatctggtgctcaactaaggcaacagcaatctgttctaccctggaggaacaattgtccatat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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