Basic Information
VIS ID
TVIS44004125
Fusion event
HTLV-1-chrY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
GRCh37/hg19
Start
15141345/13029432 (Hg38)
End
15141345/13029432 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/8423204; hsa-mir-12120/Downstream/449745;
Nearest TSS
ENST00000430575/Upstream/113936; ENST00000284856/Downstream/450072;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/124045, chrY-CpG: 33/Downstream/449947
Nearby gene
DDX3Y(+108955) ;
Upstream sequence
gggtgtgaaagtctcccattattattgtgtgggagtctaagtgtctttgtaggtctttaaggacttgccttatgaatcttgctgctcctgtattgggtgc
Downstream sequence
atatatatttaggatagttagctcttcttgtttaattgatccctttaccattatgtaatggccttctttgtttcttctgatctttgttggtttaaagtct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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