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TVIS44004128
Basic Information
VIS ID
TVIS44004128
Fusion event
HTLV-1-PTPN14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
214596809/214423466 (Hg38)
End
214596809/214423466 (Hg38)
Orient
+
Location type
Intronic
Target gene
PTPN14
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-21-5p
;
hsa-mir-324-3p
;
hsa-mir-590-5p
;
hsa-mir-3190-3p
;
hsa-mir-4491
;
hsa-mir-4657
;
hsa-mir-6833-5p
;
hsa-mir-218-5p
;
hsa-mir-450a-2-3p
;
hsa-mir-6857-5p
;
hsa-mir-6763-5p
;
hsa-mir-3150a-3p
;
hsa-mir-6810-5p
;
hsa-mir-2110
;
hsa-mir-7977
;
hsa-mir-5579-3p
;
hsa-mir-92a-1-5p
;
hsa-mir-5703
;
hsa-mir-765
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-6770-5p
;
hsa-mir-4699-5p
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4662a-3p
;
hsa-mir-3646
;
hsa-mir-3662
;
hsa-mir-302c-5p
;
hsa-mir-3143
;
hsa-mir-7853-5p
;
hsa-mir-105-5p
;
hsa-mir-342-3p
;
hsa-mir-1285-5p
;
hsa-mir-5582-5p
;
hsa-mir-451b
;
hsa-mir-5580-3p
;
hsa-mir-124-3p
;
hsa-mir-4484
;
hsa-mir-6768-3p
;
hsa-mir-130a-5p
;
hsa-mir-23a-3p
;
hsa-mir-23c
;
hsa-mir-23b-3p
;
hsa-mir-494-3p
;
hsa-mir-548aw
;
hsa-mir-6867-3p
;
hsa-mir-642a-5p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-1236-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-500a-5p
;
hsa-mir-4668-3p
;
hsa-mir-6839-3p
;
hsa-mir-4507
;
hsa-mir-3940-5p
;
hsa-mir-629-5p
;
hsa-mir-302a-5p
;
hsa-mir-195-3p
;
hsa-mir-16-2-3p
;
hsa-mir-4307
;
hsa-mir-299-3p
;
hsa-mir-33a-3p
;
hsa-mir-217
;
hsa-mir-1182
;
hsa-mir-1207-5p
;
hsa-mir-1267
;
hsa-mir-129-5p
;
hsa-mir-1304-3p
;
hsa-mir-1827
;
hsa-mir-197-3p
;
hsa-mir-3149
;
hsa-mir-3167
;
hsa-mir-3184-3p
;
hsa-mir-3612
;
hsa-mir-3664-5p
;
hsa-mir-3672
;
hsa-mir-367-5p
;
hsa-mir-411-5p
;
hsa-mir-4443
;
hsa-mir-4524a-3p
;
hsa-mir-4639-3p
;
hsa-mir-4763-3p
;
hsa-mir-483-5p
;
hsa-mir-5096
;
hsa-mir-650
;
hsa-mir-6515-5p
;
hsa-mir-6794-3p
;
hsa-mir-6808-5p
;
hsa-mir-6832-5p
;
hsa-mir-6864-3p
;
hsa-mir-6893-5p
;
hsa-mir-7850-5p
;
hsa-mir-8055
;
hsa-mir-876-5p
;
hsa-mir-940
Nearest miRNA
hsa-mir-101-1/Upstream/2345781; hsa-mir-1182/Downstream/5694387;
Nearest TSS
ENST00000473358/Upstream/47060;
ENST00000495259/Downstream/127757;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/39367
,
chr1-CpG: 124/Downstream/127295
Upstream sequence
CCCAGCCCATGTTAAGTCATATGGCTAGGCACACTTCCGGTGACCACAGACTCTGTATGGATGGGAGTGCCATCTACATTCCTTACTCCAGCATCTCTGT
Downstream sequence
CACTGTAACCATGAGCCCACTTTCCAAGTTTTGTCCCTAAGAGCCAGCCAAGCCTAACTTTAAACTTTGGTTGATGCTTTGTTTACTGGCCAGTCTAAAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL100-D
Sample type
Nontumor
Age
55
Gender
Female
CpG Island Information
×
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