Basic Information
VIS ID
TVIS44004134
Fusion event
HTLV-1-LMNTD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25691976/25539042 (Hg38)
End
25691976/25539042 (Hg38)
Orient
+
Location type
Intronic
Target gene
LMNTD1
Nearest miRNA
hsa-mir-1244-3/Upstream/1326547; hsa-let-7i/Downstream/334978;
Nearest TSS
ENST00000382841/Upstream/12886; ENST00000538081/Downstream/14202;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/152552, chr12-CpG: 155/Downstream/419216
Nearest cancer related gene
LMNTD1(TSG, No orient, 0)
Upstream sequence
actttaaaccaacaaagatcaaaagagacaaagaaggccattacataatggtaatgggatcaattcaacaagaagagctaactatcctaaatatatgtgc
Downstream sequence
acccaatacaggagcacccagattcataaagcaagtcctgagtgacctacaaagagacttcaactcccacacattaataatgggagactttaacacccca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate