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TVIS44004140
Basic Information
VIS ID
TVIS44004140
Fusion event
HTLV-1-RPL28 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
55900666/55389298 (Hg38)
End
55900666/55389298 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA19A
Target gene
RPL28
miRNAs that regulate target gene
hsa-mir-128-3p
;
hsa-mir-26b-5p
;
hsa-mir-766-3p
;
hsa-mir-18a-3p
;
hsa-mir-484
;
hsa-mir-374a-3p
;
hsa-mir-3686
;
hsa-mir-297
;
hsa-mir-361-5p
;
hsa-mir-542-3p
;
hsa-mir-4504
;
hsa-mir-567
;
hsa-mir-3649
;
hsa-mir-659-5p
;
hsa-mir-3182
;
hsa-mir-4742-3p
;
hsa-mir-1237-3p
;
hsa-mir-6754-5p
;
hsa-mir-4441
;
hsa-mir-4270
;
hsa-mir-211-3p
;
hsa-mir-4501
;
hsa-mir-1273e
;
hsa-mir-4443
;
hsa-mir-7847-3p
;
hsa-mir-6880-5p
;
hsa-mir-6851-5p
;
hsa-mir-3689d
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-6499-3p
;
hsa-mir-4722-5p
;
hsa-mir-6134
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-17-3p
;
hsa-mir-6840-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-1237-5p
;
hsa-mir-1254
;
hsa-mir-1908-5p
;
hsa-mir-3116
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-3196
;
hsa-mir-4488
;
hsa-mir-4697-5p
;
hsa-mir-637
;
hsa-mir-661
;
hsa-mir-663a
;
hsa-mir-6787-5p
;
hsa-mir-6816-5p
;
hsa-mir-6846-5p
;
hsa-mir-6848-5p
;
hsa-mir-6852-5p
;
hsa-mir-6882-3p
Nearest miRNA
hsa-let-7e/Upstream/1056; hsa-mir-10394/Downstream/2945390;
Nearest TSS
ENST00000633603/Upstream/2941;
ENST00000591164/Downstream/14846;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/2502
,
chr19-CpG: 27/Downstream/12144
Upstream sequence
attagctgggtgtggtggtgcaccgcctgtggtcccagctcctcagaggttgagtagaggctgaggtgagcggagcacttgagccaagagtatgaggctg
Downstream sequence
cagtgagcccatgagccccaccactacactccagcctggaagacaCCATGACACACAGTGAGGCCTGGATGGGGAAAGAGTCCTGCTGTTGATCCTcaca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL100-D
Sample type
Nontumor
Age
55
Gender
Female
CpG Island Information
×
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