Basic Information
VIS ID
TVIS44004142
Fusion event
HTLV-1-LOC107985321 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
18904391/18793582 (Hg38)
End
18904391/18793582 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
LOC107985321
Nearest miRNA
hsa-mir-10395/Upstream/406948; hsa-let-7e/Downstream/641481;
Nearest TSS
ENST00000633603/Upstream/2268; ENST00000601981/Downstream/38356;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2107, chr19-CpG: 104/Downstream/38041
Nearby gene
COMP(-2277) ;
Upstream sequence
GACAGGCCTATAAGTGGAGTGTTGGTGGAAGCAGCTGGTCCCAGCCAGAGCATTTCCAATGAAGCCTGTCCTCAATAGTGCCTGCCCTGCCTGCTGCCTA
Downstream sequence
CATTGGGGCCATGAGCTCACCTCCTGTTTTCCTTGGCCTTCAGCACACCTGGGGGCCGCTCCTGGCAGCACTGGAATTCTCGGGAAAACCACAGCTCCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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