Basic Information
VIS ID
TVIS44004143
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
GRCh37/hg19
Start
46447204/46220065 (Hg38)
End
46447204/46220065 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/10748579; hsa-mir-10b/Downstream/1157610;
Nearest TSS
ENST00000437798/Upstream/52087; ENST00000460015/Downstream/73602;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/567519, chr2-CpG: 289/Downstream/76585
Nearby gene
PRKCE(+32075) ;
Nearest cancer related gene
PRKCE(TSG, +32075) ;
Upstream sequence
aaacagactttaaaccaacaaagatcaaaagagacaaacaaggccactatataatggtaaagggatcaattcaacaagaagagctaactatcctagatat
Downstream sequence
atatgcacccaatacaggagcacccagattcataaggcaagtccttagagacctacagagagacttagactcccacacagtaataatgggagactttaac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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