Basic Information
VIS ID
TVIS44004147
Fusion event
HTLV-1-LOC105372813 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
43092334/41672174 (Hg38)
End
43092334/41672174 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372813
Nearest miRNA
hsa-let-7c/Upstream/504545; hsa-mir-5692b/Downstream/74598;
Nearest TSS
ENST00000624081/Upstream/90855; ENST00000413718/Downstream/7007;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/163427, chr21-CpG: 32/Downstream/17015
Nearby gene
LINC00111(+7128) ;
Upstream sequence
GCCTGTGGGTCCTTCTGAGAGGCTGCCCTCAAGAGCAGGTATGAGAGTGAGTGAGTGCACAGCCTGAATCCGGCTCAATGAAGACAAAGATGATGGTGAG
Downstream sequence
AAAAGTGTCCATGAGCCCTTGGAGAAAACCCTCTCCAGCAAGAGGGACACCTTAGCCACCTGTGGCCTGGCCCGGATCACCTGAGCAGGCCACTGCCAGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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