Basic Information
VIS ID
TVIS44004156
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
110326654/107564373 (Hg38)
End
110326654/107564373 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7a-1/Upstream/963351; hsa-mir-12126/Downstream/1481856;
Nearest TSS
ENST00000422679/Upstream/73891; ENST00000333999/Downstream/690447;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/73994, chr9-CpG: 50/Downstream/73247
Nearby gene
KLF4(-74653) ;
Nearest cancer related gene
KLF4(TSG, -74653) ;
Upstream sequence
CATGAAAAAGGAAAAGAGGGAAGGAGGAGAGTGAGCTTTGTGCCTTCTGGGAAGTCAGAGGGGTAGGAAGTCACTTAACCTCCACACATGACAACCTAGG
Downstream sequence
GACAGTCCCCATGAGCCTGAGAGGATGCTGACCACCAGGAGTCTAGAATGCTCAGAGCTGGCACGGGGGGTCTGAACAACTGAGAAAAATCTGCTTGCTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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