Basic Information
VIS ID
TVIS44004201
Fusion event
HTLV-1-LOC102723546 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
130523222/131389248 (Hg38)
End
130523222/131389248 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC102723546
Nearest miRNA
hsa-let-7f-2/Upstream/10018195; hsa-mir-105-1/Downstream/2780130;
Nearest TSS
ENST00000429181/Upstream/99819; ENST00000338616/Downstream/154728;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/306320, chrX-CpG: 26/Downstream/406657
Nearby gene
IGSF1(-99819) ;
Upstream sequence
CTAGAAACCAAAGAGGATCATGAGAAAGAGAAGTAGTCAGGGAATCAGGTCAGAGACAAGGAAACAAACAAAGGATTGGAAGGCTCATGGATTCATAGCA
Downstream sequence
ACCAAAACTTCAAGTAGTTTAGATATTATgcctgcctagattcagagcccctgctcttcccactgtattatatttctcTATGAGAAATTTTTAAAATGGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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