Basic Information
VIS ID
TVIS44004207
Fusion event
HTLV-1-FBLN7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
112964724/112207147 (Hg38)
End
112964724/112207147 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
FBLN7
miRNAs that regulate target gene
hsa-mir-377-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/436013; hsa-mir-10b/Downstream/1375812;
Nearest TSS
ENST00000437798/Upstream/25264; ENST00000476511/Downstream/24738;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/19702, chr2-CpG: 67/Downstream/47384
Nearby gene
ZC3H8(-8715) ;
Upstream sequence
aatctacttccattatgtacagagaatagactttgaattatttcaatacttttaaatttgttaagttttattttatgacccaagatatggtttatcttag
Downstream sequence
tcaatgctccatgagcacttgaaaagaacgtgtatttggccaggcaaggtggctcatgcctgtaatcccagtactttgggaggcagaggcaggcggatca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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