VISDB Viral Integration Site DataBase

VIS ID

TVIS44004222

Fusion event

HTLV-1-DPYSL5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

p23.3

Reference genome

Start

End

27172271/26949403 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-130b-5p ; hsa-mir-186-5p ; hsa-let-7b-5p ; hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-7150 ; hsa-mir-6867-5p ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-3665 ; hsa-mir-4736 ; hsa-mir-125a-3p ; hsa-mir-4524b-3p ; hsa-mir-4707-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-4425 ; hsa-mir-92a-1-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-1178-5p ; hsa-mir-1281 ; hsa-mir-4713-5p ; hsa-mir-7111-3p ; hsa-mir-3156-3p ; hsa-mir-6809-5p ; hsa-mir-31-5p ; hsa-mir-4749-3p ; hsa-mir-3128 ; hsa-mir-7110-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-6787-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-6892-3p ; hsa-mir-4301 ; hsa-mir-483-3p ; hsa-mir-6769a-3p

Nearest miRNA

hsa-mir-1301/Upstream/1620682; hsa-mir-10b/Downstream/1046964;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/99349, chr2-CpG: 74/Downstream/21002

Upstream sequence

ACTTCTCCCTTCACTCCCCCTTTCCTCACTCAGGGGCTGAGAGGACAGAGGTGGTCAGCCGGGGAGCAGAGGTGGCGAAGGGGCTCATGGCAAGTGGCAG

Downstream sequence

CCATTGGAACAGGGGTGAGGACCCAGGCCTGGGAAAGCCACCAGGGATGGGGGAAACCATGACGCCGCCTCCTGGTGCAGTGCACACCATCTCTATCCCT