Basic Information
VIS ID
TVIS44004238
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.23
Reference genome
GRCh37/hg19
Start
119137171/118699366 (Hg38)
End
119137171/118699366 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12E ; FRA12C
Nearest miRNA
hsa-let-7i/Upstream/2271048; hsa-mir-1178/Downstream/1014268;
Nearest TSS
ENST00000382841/Upstream/50642; ENST00000545224/Downstream/62291;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/322332, chr12-CpG: 29/Downstream/74939
Nearby gene
SUDS3(+281331) ;
Upstream sequence
ctcatatattttaaatcaagaAAAGGTTCAAAAGGATGTCAATGGTGCTTATTTATGGACTTTTTTACTTGCCCACTAAAAGTTTTTAAAATAAGCATTT
Downstream sequence
ATTGTCAAGAAGAAAGAATAAGAAATCACTTCtatattggcttggattgcttttggctgcaaataagagaaaatctaacagtggcttagacagaaaatgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate