Basic Information
VIS ID
TVIS44004239
Fusion event
HTLV-1-ZNF337-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
25605478/25624842 (Hg38)
End
25605478/25624842 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ZNF337-AS1
Nearest miRNA
hsa-mir-103a-2/Upstream/7154151; hsa-mir-1-1/Downstream/583344;
Nearest TSS
ENST00000382410/Upstream/609; ENST00000421829/Downstream/7368;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/291, chr20-CpG: 107/Downstream/71222
Upstream sequence
GCCTTTTAAACCCGCGGAAGGGCTGTAGCAACTCTTGTCTCCTAGTGCTGGCAGAACGGGGATCGTAACACTAATCTCTAATCTTTGTCTCTCTTGGGTA
Downstream sequence
CCTTTACTGTAATTTGGATATGTGGTCATCATTAGTGACCAGAAATTGACTGTCAGGTACAggccaattacctgattttgtttagccagtgagctaagtg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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