Basic Information
VIS ID
TVIS44004247
Fusion event
HTLV-1-C6orf203 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
107371605/107050401 (Hg38)
End
107371605/107050401 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6F
Target gene
C6orf203
Nearest miRNA
hsa-mir-10398/Upstream/266181; hsa-mir-1202/Downstream/12018646;
Nearest TSS
ENST00000381078/Upstream/10409; ENST00000618129/Downstream/64031;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/21885, chr6-CpG: 98/Downstream/18357
Upstream sequence
GAAATTGTCTTCACTGTGCATGTAGTAATTACTGTGCACACAGTCTCTAAGACTGCCCCCACTTTCTTTGTCTTTTGCCAGTGTTACCAAGATAAATGTG
Downstream sequence
TCCATTCAAATATTTCCTTAAGTCACCCAATAGATGTGAGTATTTGAGCTACTCTGCGCAGGGACTATCCACAGCCAGCCAGTTGTCTAGTTCTGAAGGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate