Basic Information
VIS ID
TVIS44004263
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
157525595/157555805 (Hg38)
End
157525595/157555805 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/619561; hsa-mir-1182/Downstream/2344174;
Nearest TSS
ENST00000473358/Upstream/3285; ENST00000453692/Downstream/24732;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/360460, chr1-CpG: 28/Downstream/423125
Nearby gene
FCRL5(-3285) ;
Upstream sequence
tattggtctcataagcaagctccttctttttctattttcgtgaagagtttgtgtacgactgatgttatttcttccttaaatgtttggaagattttactgg
Downstream sequence
taaagGTACTTACTTAGGCTTatgaaaaaatgctcaccatcactggccatcagagaaatgcaaatcaaaaccacaatgagatatcatctcacaccagtta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate