Basic Information
VIS ID
TVIS44004270
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
139386389/138628819 (Hg38)
End
139386389/138628819 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-128-1/Upstream/2963341; hsa-mir-10b/Downstream/1957807;
Nearest TSS
ENST00000437798/Upstream/24309; ENST00000429008/Downstream/151529;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/126477, chr2-CpG: 96/Downstream/151303
Nearby gene
NXPH2(-40338) ;
Upstream sequence
CTGGAAAAATCATATGTTCACCACATGAAACCTTtccaaatgacccttctcatttgtcttcccaaaaaattttatacattcttaattactattaacatca
Downstream sequence
cgttgtattatatttagttgtttatttatctcgctgcattgataggctgtgaactcctcaagggtaagATGTGAGGGGATGtgttcagaggactaaatgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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