Basic Information
VIS ID
TVIS44004273
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74434321/73568604 (Hg38)
End
74434321/73568604 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/7291676; hsa-mir-1243/Downstream/3004964;
Nearest TSS
ENST00000502981/Upstream/58393; ENST00000436089/Downstream/51808;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/309191, chr4-CpG: 20/Downstream/51723
Nearby gene
RASSF6(-2946) ;
Upstream sequence
tctggcccagggagtgtctagaaatgttgtcagggtttagggcctggaatgggggtctcatgactctgcctggtgctccatcctattgtcggtgagctag
Downstream sequence
taaccaagatgcaagtcaaaattcttttgattcttccttcttccctcctcaagcacaaggaaggagtcactttagttgttgtaagctgtgcagcctatgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate