Basic Information
VIS ID
TVIS44004293
Fusion event
HTLV-1-COL15A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
101820008/99057726 (Hg38)
End
101820008/99057726 (Hg38)
Orient
+
Location type
Intronic
Target gene
COL15A1
miRNAs that regulate target gene
hsa-mir-29c-3p ; hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-29b-3p
Nearest miRNA
hsa-let-7a-1/Upstream/828509; hsa-mir-12126/Downstream/7543202;
Nearest TSS
ENST00000422679/Upstream/19053; ENST00000548365/Downstream/46312;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/71925, chr9-CpG: 142/Downstream/46986
Upstream sequence
gaacctttccaaggtcacacagctaataagtgacaccaacaggattcagacccagagcagtgtagctccaaagcctgtgttatttctactATGTCCATTG
Downstream sequence
GAGGAGACAATAATAGCAGCAATAATAGCATGAAGGCATACTTTTTTGTTGTTTGGCTTGGCAGGAGCCAGGTATGGTGGAAGCATACCTGGAAAGAGAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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