Basic Information
VIS ID
TVIS44004300
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
95358634/95639790 (Hg38)
End
95358634/95639790 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/8413513; hsa-mir-12124/Downstream/720174;
Nearest TSS
ENST00000440867/Upstream/676860; ENST00000506569/Downstream/978446;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/701475, chr3-CpG: 49/Downstream/1136983
Nearby gene
MTHFD2P1(No orient, 14633)
Upstream sequence
TTATATTTTATTACTTTGTTTTTGTTTGATGCATAATGATTATGTCTTCCCAAATATATAATTACTTGATAAATAGCTAACTGAGATGCTGTCATATTGT
Downstream sequence
AGAAGGAAAACAAAATACTAAATTACACAAGATTTAATACGTTTATACCCTAGTCCTCCAACAGGCTTTTGTTTGTTTGTTtgtttaatcatggaaacag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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