Basic Information
VIS ID
TVIS44004319
Fusion event
HTLV-1-MIR4300HG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
81773700/82062658 (Hg38)
End
81773700/82062658 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MIR4300HG
Nearest miRNA
hsa-mir-10392/Upstream/171822; hsa-let-7a-2/Downstream/4215675;
Nearest TSS
ENST00000527297/Upstream/91664; ENST00000526305/Downstream/37385;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2621498, chr11-CpG: 25/Downstream/626885
Upstream sequence
ttggcattaccattaagagtggatgagagtttcagttttttcttatcctcatcaacactcagtattttcagtcttcctaattagccattttggtgggtat
Downstream sequence
agagtagcactgacttatagttttaatttgcatttctaactaactaatgaaaataattcatttttcagatgttaacttgccagtggggtatcctaatttg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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