Basic Information
VIS ID
TVIS44004322
Fusion event
HTLV-1-LMO7-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
76205415/75631279 (Hg38)
End
76205415/75631279 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA13E
Target gene
LMO7-AS1
Nearest miRNA
hsa-mir-1297/Upstream/9412955; hsa-mir-1267/Downstream/2066733;
Nearest TSS
ENST00000623511/Upstream/8009; ENST00000465309/Downstream/4531;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/81147, chr13-CpG: 175/Downstream/4125
Upstream sequence
ccatgcccagctaatttttgtatttttagtaggggtttcaccatgttacccaggctggtcttgaactgccgagcttgagcaatctacccgccttggcctc
Downstream sequence
ccaaagtgctgggattacaggtgtgagccaccgcaactggcctccttttacattcttaatgactgcacaatatctcactatggaggaaccataatttact
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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