Basic Information
VIS ID
TVIS44004366
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
19051714/19071070 (Hg38)
End
19051714/19071070 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA20A
Nearest miRNA
hsa-mir-103a-2/Upstream/600379; hsa-mir-1-1/Downstream/7137116;
Nearest TSS
ENST00000382410/Upstream/14274; ENST00000613834/Downstream/141576;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/482622, chr20-CpG: 155/Downstream/140745
Nearby gene
SLC24A3(+141576) ;
Upstream sequence
TAATTTTCATAAAATAAgcaaaggagaaagaacgtggcttcagggtcagaaaatactgggtttaagtcaaggctttgctttgagaggttctaaagggtat
Downstream sequence
gactttggggaagttgcaaactcttggggagattcaactttcctcttctgtaagctaggaaccagagtgactatccctcagggctttgaggaagttaaat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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