Basic Information
VIS ID
TVIS44004382
Fusion event
HTLV-1-LOC105377458 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
144748791/143827638 (Hg38)
End
144748791/143827638 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377458
Nearest miRNA
hsa-mir-12113/Upstream/484103; hsa-mir-1305/Downstream/2580945;
Nearest TSS
ENST00000502981/Upstream/126963; ENST00000568324/Downstream/77881;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/126573, chr4-CpG: 91/Downstream/817452
Nearby gene
GYPE(-43228) ;
Upstream sequence
cgtctagctcctgagcagctgggactacagatgtgctccaccacagctggctaattttgtttgtttatttatttatttatttgtttacttatttgtttat
Downstream sequence
ttattgagacaaggtctcactatgttgcccaggcttgtctccaactcctggactcaagtgaccctcctgccttcacctccaaaagtgctagggttacagg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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