VISDB Viral Integration Site DataBase

VIS ID

TVIS44004422

Fusion event

HTLV-1-ARID5B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q21.2

Reference genome

Start

End

63747129/61987370 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-22-3p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-1277-5p ; hsa-mir-3653-3p ; hsa-mir-3658 ; hsa-mir-5011-5p ; hsa-mir-186-3p ; hsa-mir-320a ; hsa-mir-373-5p ; hsa-mir-576-3p ; hsa-mir-616-5p ; hsa-mir-767-3p ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-4426 ; hsa-mir-4429 ; hsa-mir-4491 ; hsa-mir-4647 ; hsa-mir-4657 ; hsa-mir-4662b ; hsa-mir-371b-5p ; hsa-mir-6833-5p ; hsa-mir-570-5p ; hsa-mir-3692-3p ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-4476 ; hsa-mir-4694-3p ; hsa-mir-5692a ; hsa-mir-6876-5p ; hsa-mir-548ba ; hsa-mir-33a-5p ; hsa-mir-185-5p ; hsa-mir-432-5p ; hsa-mir-33b-5p ; hsa-mir-1284 ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-5192 ; hsa-mir-6813-3p ; hsa-mir-583 ; hsa-mir-573 ; hsa-mir-3156-5p ; hsa-mir-3616-5p ; hsa-mir-4670-3p ; hsa-mir-190a-3p ; hsa-mir-656-3p ; hsa-mir-4795-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-3190-3p ; hsa-mir-7856-5p ; hsa-mir-552-3p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-140-3p ; hsa-mir-4482-3p ; hsa-mir-152-5p ; hsa-mir-597-3p ; hsa-mir-182-3p ; hsa-mir-4680-5p ; hsa-mir-126-5p ; hsa-mir-218-2-3p ; hsa-mir-3928-3p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-324-5p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-6743-5p ; hsa-mir-4688

Nearest miRNA

hsa-mir-1265/Upstream/4682811; hsa-mir-107/Downstream/1385587;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/83830, chr10-CpG: 67/Downstream/280912

Upstream sequence

GAGTAGGATGAGAACAGAGGGACAGTGAATAACCAGAAAAAGaaccaacattaattaaaaatctatcatgtgcttcgcttgtttccagggtgttaggaat

Downstream sequence

tcagacatgctacagacctagctcctgcccttcaaagaacccatattctggaaaggagagtccagcttgaacaagtaaatgcagccaagtgttacagagt