Basic Information
VIS ID
TVIS44004442
Fusion event
HTLV-1-LOC105376942 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p26.1
Reference genome
GRCh37/hg19
Start
6138427/6096740 (Hg38)
End
6138427/6096740 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105376942
Nearest miRNA
hsa-mir-4790/Upstream/846485; hsa-let-7g/Downstream/4183611;
Nearest TSS
ENST00000440867/Upstream/133898; ENST00000435651/Downstream/51744;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/908235, chr3-CpG: 71/Downstream/764396
Nearby gene
GRM7-AS3(No orient, 535618)
Upstream sequence
CTCTATTACATAGCTCACTGTTCCATCCTTTCCTGCCAAGTTTACTTTCAAGATGTGATTAAGGGGTGTTCTATACATTGAAAGACATTCCTTCTCTGTG
Downstream sequence
TAGAGCAGAAAACCAAAGAAAAACAGTAGTATTTTTCAATATGTCCCATGACCTGTTGTAATATTATATTTTAAAAGGACTTAATTGTAAAAAATACATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate