Basic Information
VIS ID
TVIS44004459
Fusion event
HTLV-1-LOC107984893 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
18033850/17939993 (Hg38)
End
18033850/17939993 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107984893
Nearest miRNA
hsa-mir-1225/Upstream/1571051; hsa-mir-11401/Downstream/404020;
Nearest TSS
ENST00000527434/Upstream/114741; ENST00000549796/Downstream/32549;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/468988, chr16-CpG: 18/Downstream/397315
Nearby gene
NPIPA8(No orient, 377926)
Upstream sequence
AAGTTTAAATGAGATGGCTCTTCTGCAGGCTTCAACCGCAGCAGCTCCATCTGACATGCTTTAAATATTTCAGTTTTGCATATGTCATGTGATACATTCG
Downstream sequence
GACAttttctattttctttcttttttgagacagggtctcactctggtcacccaggctggagtgcagtggtacaatcatagctcactgcagcctcagtttc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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