Basic Information
VIS ID
TVIS44004460
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
157215154/156358642 (Hg38)
End
157215154/156358642 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-128-1/Upstream/4990231; hsa-mir-10b/Downstream/2828193;
Nearest TSS
ENST00000437798/Upstream/16294; ENST00000416888/Downstream/76648;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/15808, chr2-CpG: 31/Downstream/41654
Nearby gene
NR4A2(-25867) ;
Upstream sequence
TTTGCATTTTTAAGAAGAACTCTTGAAGACCTATTGTTAGCAGTCAAAATGTCACATCTTTCTGTCTGTCAAGAATGGCAAAAATCCATATTTTACAATA
Downstream sequence
ACTGGCTTTTACTTATTGATTCTACCCAGCTTAAAATGTGTTTCTGAagcataatgagatagagattaagatcaagggctttgtagtcagacagacctag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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