Basic Information
VIS ID
TVIS44004461
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
216107704/215242981 (Hg38)
End
216107704/215242981 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/1484822; hsa-mir-1244-1/Downstream/2657532;
Nearest TSS
ENST00000437798/Upstream/104553; ENST00000448086/Downstream/32011;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/432653, chr2-CpG: 62/Downstream/68845
Nearby gene
ATIC(+68975) ;
Upstream sequence
atcacccttcccacaaacccaatcctgtaacagattctattaatttaaccaggaaaatctatctacttctccctaaacccatagtcatcaccttagttcc
Downstream sequence
ttagtccaagccagcattatttcttttccagatgactgcaatagctgcctaactatctcctatctccctgcactcactcttgcttcctataccccattct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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