Basic Information
VIS ID
TVIS44004475
Fusion event
HTLV-1-CPE integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
End
166352853/165431701 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-17-5p ; hsa-mir-129-5p ; hsa-mir-544a ; hsa-mir-379-3p ; hsa-mir-485-5p ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-765 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-3185 ; hsa-mir-7515 ; hsa-mir-5584-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-3154 ; hsa-mir-5197-3p ; hsa-mir-8055 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6879-3p ; hsa-mir-4524a-3p ; hsa-mir-6773-3p ; hsa-mir-5007-5p ; hsa-mir-4797-5p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-182-5p ; hsa-mir-7150 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-1972 ; hsa-mir-383-3p ; hsa-mir-7703 ; hsa-mir-8064 ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6847-3p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6778-3p ; hsa-mir-4740-3p ; hsa-mir-106a-3p ; hsa-mir-3622b-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4327 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-5197-5p ; hsa-mir-1537-5p ; hsa-mir-3607-3p ; hsa-mir-3609 ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-4685-3p ; hsa-mir-4780 ; hsa-mir-518a-5p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-527 ; hsa-mir-548ah-5p ; hsa-mir-548aw ; hsa-mir-623 ; hsa-mir-6780b-3p ; hsa-mir-6841-3p ; hsa-mir-6867-3p ; hsa-mir-7113-3p
Nearest miRNA
hsa-mir-12113/Upstream/45364; hsa-mir-1305/Downstream/5754483;
Upstream sequence
TGCTGCTTCCTGATGAGTTTGGAACATCCCCAGTGGACAGATTCTGGTTTTTTCTGTATATATTATATAATCATGGTAATTGAAATTAAGTACTGAAGAA
Downstream sequence
CTTTTGGAACTTTTTGGCAGAGATATCTGAAAGCTGATTTGATTTTTGTTGAAGTATGAAGACAGTAAAATATGGTAAAGTGTGATAAGGAGCCACAGAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate