Basic Information
VIS ID
TVIS44004481
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
25709844/27382818 (Hg38)
End
25709844/27382818 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/88822; hsa-mir-10226/Downstream/977836;
Nearest TSS
ENST00000595228/Upstream/49562; ENST00000579309/Downstream/73652;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/28770, chr17-CpG: 141/Downstream/73255
Nearby gene
TBC1D3P5(No orient, 35187)
Upstream sequence
TCAGCCAGTGTTATAAGTAGCTGGGAATATAAAAGTTGGGCAGGGAGAGCAGAATCCAGCTTGGTCCTGGGCTGGGAAACATGGATTGGGGGTGGGGGGA
Downstream sequence
TAGTGGCTGGTCTGGTACCAGGCTTATGGTTTGCTGGAAAGATCTGTCTCCTCCAGCAACAGCTGTGAGAGAGAGCTGGGTTGTGAACTACCCTGCAGGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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