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Viral Integration Site DataBase
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TVIS44004502
Basic Information
VIS ID
TVIS44004502
Fusion event
HTLV-1-SOX6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
16486941/16465394 (Hg38)
End
16486941/16465394 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11C
;
FRA11I
Target gene
SOX6
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-499a-5p
;
hsa-mir-155-5p
;
hsa-mir-16-5p
;
hsa-mir-208a-3p
;
hsa-mir-3148
;
hsa-mir-4668-5p
;
hsa-mir-562
;
hsa-mir-651-3p
;
hsa-mir-548n
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-1269a
;
hsa-mir-132-3p
;
hsa-mir-202-3p
;
hsa-mir-1273h-5p
;
hsa-mir-129-5p
;
hsa-mir-30b-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-30c-2-3p
;
hsa-mir-3122
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-3913-5p
;
hsa-mir-450a-1-3p
;
hsa-mir-6513-5p
;
hsa-mir-6731-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6788-5p
;
hsa-mir-6878-5p
;
hsa-mir-8085
;
hsa-mir-887-5p
Nearest miRNA
hsa-mir-210/Upstream/495773; hsa-let-7a-2/Downstream/1922393;
Nearest TSS
ENST00000527297/Upstream/30944;
ENST00000525106/Downstream/10994;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/523717
,
chr11-CpG: 101/Downstream/139112
Upstream sequence
GCCTCTGCCAGGACAAATCTCAGAATGTTTTAATCCCTTAAAACTGCCAGCTGTCCAATGAGCATACACTTACTACTATGTCAGATATCAAAATATGTGA
Downstream sequence
GATCAATCTCACCTTTAAAACAATCCATTCTGATTAATGATTCTACTATATATATATAATAATGGAAAAAAATACATCTGGATTTCTTCATTTTGTTCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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