Basic Information
VIS ID
TVIS44004516
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
68401214/70405073 (Hg38)
End
68401214/70405073 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/1305417; hsa-mir-1250/Downstream/4343540;
Nearest TSS
ENST00000595228/Upstream/36157; ENST00000442627/Downstream/374157;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/235494, chr17-CpG: 26/Downstream/1710765
Nearby gene
KCNJ2(+225031) ;
Upstream sequence
taggtggagaccattcgttttttcaccactgaactacaaggcatggttatgaattatgaatataacacagttgattagtcccgttgttcacatgacatgt
Downstream sequence
ggcttagttccaggttgttttgcttttgttattacaaaTGTTTTTCTTAAATCCGTGAGTTCCACAATCTATTTTCTCTCTGCCTGCTGTTTTATATTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate