Basic Information
VIS ID
TVIS44004521
Fusion event
HTLV-1-MLLT10P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.21
Reference genome
End
29637832/30403156 (Hg38)
Orient
+
Location type
ncRNA_exonic
Target gene
Nearest miRNA
hsa-mir-103a-2/Upstream/4194878; hsa-mir-1-1/Downstream/1204030;
Upstream sequence
CTTTTACAAAGCATAACTATTAATATTATTGACCATCATAAGAGCAAATATTTTAAGTAAAACACCATAAATACTTTACAGAAAGGAGCGAGTTGCAGAC
Downstream sequence
ACAGTCATTCTTGGATTTCTTTCAACACCAGGCTTTCTTCCCTTTTGACCTGAACTGGGAGTTGAATATTGCCTCTCTTTGCCTTCTGACCCTCTAGTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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