Basic Information
VIS ID
TVIS44004534
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
60459171/60065390 (Hg38)
End
60459171/60065390 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1228/Upstream/2240698; hsa-let-7i/Downstream/2194969;
Nearest TSS
ENST00000382841/Upstream/296331; ENST00000552378/Downstream/27474;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/468664, chr12-CpG: 117/Downstream/2125597
Nearby gene
SLC16A7(+275536) ;
Upstream sequence
GACTATCTCTGAAATACACATATATACATAGCCCCAGTTTTATGTCATATAATTTTTGTCTTCTTTCCCTTAAAATCTAAGAAGCTCATTCATAAAAAAC
Downstream sequence
AAATTCATAATAACTAAAATTTCCAAATAAGAAGTCAGAAAAATGCAAATATTCTTTCTCATAATATTACCTTAAATTACACATACTGCATAATCAACAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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