Basic Information
VIS ID
TVIS44004542
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
62995573/65328337 (Hg38)
End
62995573/65328337 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/6877179; hsa-mir-5011/Downstream/1753247;
Nearest TSS
ENST00000575820/Upstream/142178; ENST00000582028/Downstream/95676;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1325316, chr18-CpG: 88/Downstream/422263
Nearby gene
CDH7(+421915) ;
Upstream sequence
TCCTAACTTCATGAAGTTTAGGTTAACATAAACATTATATTTTGAAGAGTTTCTTTTTTGCTTCTTTTAGTAACTGAAAAGTGAAAACTAAGTGGTTTAA
Downstream sequence
TAGCAAACTTTTCCTTATTAAGGAATTTTAAACAAAGGATATTTTAGTTTCTAAAATAGAAGAAAGCATCACTTGCAGTTTAAGCTATCGAGAATGGCTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate