Basic Information
VIS ID
TVIS44004553
Fusion event
HTLV-1-MIR29B2CHG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
207976027/207802682 (Hg38)
End
207976027/207802682 (Hg38)
Orient
-
Location type
Intronic
Target gene
MIR29B2CHG
Nearest miRNA
hsa-mir-101-1/Upstream/159; hsa-mir-1182/Downstream/1629451;
Nearest TSS
ENST00000473358/Upstream/32343; ENST00000638446/Downstream/20021;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/50063, chr1-CpG: 94/Downstream/65835
Nearby gene
MIR29B2(-159) ;
Upstream sequence
AGGAGAAATATCTTCTTGTAGTTCTACTTGTGATATGACACAGTGCTCCATGGGAAAGGCACAGAGGAGGTTACACAGGGCTGCACAAGGCAACATGAAA
Downstream sequence
GGCACAGCTGATGCTTCAAATAGATGAGAGCAATACAAAACTCATTAATTCTAGGTTAATTCTATTTAACTTCACACCAGTCACTACAAATTATTATATA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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